Ultimate Homemade Italian Meatball Subs: A Flavorful Family Favorite
Prepare yourself for an unforgettable culinary experience with these incredible homemade Italian meatball subs. Each bite is a symphony of flavors and textures: irresistibly juicy meatballs, bathed in a rich, robust marinara sauce, all crowned with perfectly melted fresh mozzarella cheese, nestled inside a warm, toasty bun. This isn’t just dinner; it’s a taste of pure heaven that brings the authentic flavors of Italy right to your kitchen.
Our secret to truly exceptional meatball subs lies in the homemade meatball mixture. We combine tender ground beef with savory Italian sausage and a careful blend of seasoned bread crumbs and spices. This dynamic duo of meats ensures maximum flavor and a wonderfully tender texture. For ultimate convenience without sacrificing taste, we recommend using your favorite high-quality jarred marinara sauce, though a homemade version elevates it further. And for the crowning glory? Slices of fresh mozzarella, which, in our opinion, is absolutely the best cheese for meatball subs, melting into a creamy, stretchy perfection. A quick bake in the oven, and a hearty, satisfying dinner is ready to be devoured!
Wondering what to serve alongside these magnificent meatball subs to complete your meal? We’ve got you covered with a selection of refreshing and easy side dishes. Consider pairing them with a light and zesty Creamy Cucumber Salad, a crisp and savory Broccoli Caesar Salad, or a vibrant Fruit Salad Cocktail. These sides offer a perfect contrast, complementing the richness of the subs without overpowering them, ensuring a balanced and delightful spread for your family or guests.

Why This Meatball Sub Recipe Will Be Your New Go-To
- Effortless & Flavorful Homemade Meatball Subs: While store-bought frozen meatballs offer convenience, this recipe elevates the classic meatball sub to a whole new level of deliciousness, all without excessive effort. Our homemade Italian sausage meatballs are surprisingly simple to prepare, making them a perfect weeknight project or a fun weekend cooking session. The process is straightforward: mix the meatballs, sear them to lock in flavor, simmer them in sauce, assemble your subs, give them a quick toast, and serve. The result is a meal that tastes like it took hours, but comes together with ease, making it an ideal choice for a satisfying family dinner.
- The Best Italian Meatball Recipe You’ll Ever Make: We understand the appeal of frozen meatballs for their sheer convenience, and there’s certainly a time and place for them. However, once you try these homemade Italian meatballs, infused with the rich, savory depth of Italian sausage and perfectly seasoned, you’ll find them absolutely irresistible. The blend of ground beef and Italian sausage creates a texture that’s both tender and moist, while the carefully selected spices sing with authentic Italian flavor. These aren’t just meatballs; they’re the heart of an extraordinary sandwich, guaranteed to become your new favorite and a cherished recipe in your culinary repertoire.
Key Ingredients for the Perfect Meatball Sub
- Italian Sausage: This ingredient is a game-changer for our meatballs, infusing them with incredible depth of flavor and a wonderful aromatic quality. Italian sausage comes pre-seasoned with a blend of fennel, garlic, and other spices, which means less work for you and maximum impact in every bite. We typically use mild Italian sausage for a universally appealing flavor, but if you enjoy a kick, feel free to opt for hot Italian sausage or add a pinch of red pepper flakes to the meat mixture for an extra spicy note. It beautifully complements the ground beef, ensuring the meatballs are never bland.
- Ground Beef: The ground beef component balances the rich seasoning of the Italian sausage, preventing the meatballs from becoming overwhelmingly salty or overly spiced. For the juiciest meatballs, we recommend using ground beef with an 80/20 fat ratio (80% lean, 20% fat), as the fat renders during cooking, keeping the meatballs moist and tender. However, you can certainly use whatever fat percentage you have on hand. For a lighter, healthier twist, you can easily substitute ground turkey to create delicious turkey meatball subs, adjusting seasonings as needed to maintain flavor.
- Bread Crumbs: It might seem counterintuitive to add breadcrumbs to meat, but they are a critical ingredient for achieving tender, moist meatballs. Breadcrumbs act like tiny sponges, absorbing the juices and moisture released by the meat as it cooks. This crucial step prevents the meatballs from drying out, ensuring they remain succulent and flavorful on the inside. We use seasoned bread crumbs in this recipe for an extra layer of Italian flavor, but plain bread crumbs work just as well – simply ensure your other seasonings are on point. You could also try panko breadcrumbs for a slightly lighter texture.
- Marinara Sauce: The foundation of any great meatball sub is a stellar marinara sauce, and it’s truly the best sauce for meatballs. Its bright, tangy tomato flavor and subtle sweetness perfectly complement the savory meatballs. For the easiest meatball subs, we highly recommend using your favorite brand of jarred marinara sauce. High-quality brands like Rao’s offer exceptional flavor with minimal effort. If you’re feeling ambitious and want to take your subs to an even higher level, our Pizza Sauce recipe or a simple homemade marinara would be absolutely phenomenal.
- Fresh Mozzarella: We are unabashedly in love with fresh mozzarella, and for good reason! Its creamy texture and mild, milky flavor, combined with its incredible meltability, make it the ultimate cheese for topping meatball subs. When heated, it transforms into a gooey, stretchy layer that perfectly hugs the meatballs and sauce. While provolone or shredded parmesan would also be tasty, fresh sliced mozzarella truly delivers that authentic, luxurious Italian sub experience.
- Sub or Hoagie Rolls: You can’t have a meatball sub without the perfect vessel! Sturdy sub rolls or hoagie buns are essential. Look for rolls that are soft on the inside but have a good crust on the outside to hold up to the generous filling of meatballs and sauce. The ideal roll provides structure without being too dense. If traditional sub or hoagie rolls are unavailable, a good quality hot dog bun can work in a pinch, or even a crusty French bread baguette sliced lengthwise. Toasting the bread before assembly is a non-negotiable step to prevent sogginess and add a delightful crunch.
- Spices and Herbs: Beyond the seasoned bread crumbs and Italian sausage, we incorporate Italian seasoning, garlic powder, onion powder, salt, and black pepper. These spices are carefully chosen to enhance the natural flavors of the meat and contribute to that classic Italian-American profile, ensuring every meatball is bursting with savory goodness. A fresh garnish of basil or parsley after baking adds a final touch of brightness and aromatic appeal.

Step-by-Step Guide: Crafting Your Perfect Italian Meatball Subs
- Prepare the Flavorful Meatball Mixture: In a spacious medium-sized mixing bowl, combine 1 pound of ground beef (preferably 80/20 for optimum juiciness), 8 ounces of Italian sausage (mild or hot, depending on your preference), ½ cup of seasoned bread crumbs (these are key for tenderness!), 2 teaspoons of Italian seasoning, 1 large egg (acting as a binder), 1 teaspoon of salt, and a ½ teaspoon each of freshly ground black pepper, garlic powder, and onion powder. Gently mix all the ingredients until just combined. Be careful not to overmix, as this can lead to tough meatballs. Once mixed, portion the meat mixture into uniform 1-inch meatballs. You should yield approximately 32 delicious meatballs from this batch.
- Heat Your Skillet to Perfection: Place a large skillet (a nonstick pan or a well-seasoned cast iron skillet works best) over medium heat on your stovetop. Add 2 tablespoons of olive oil to the skillet. Allow the oil to heat up until it shimmers slightly, indicating it’s ready for searing. This initial heat is crucial for achieving a beautiful brown crust on your meatballs.
- Sear the Meatballs for Enhanced Flavor: Carefully add your prepared meatballs to the hot skillet. To avoid overcrowding the pan, you may need to work in batches. Sear the meatballs for 3-4 minutes on each “side” (aim for browning on at least 3-4 surfaces of each meatball). Searing is a vital step as it locks in the juices, develops a rich, caramelized crust, and adds a significant depth of flavor that simmering alone cannot achieve. Once beautifully browned, remove the meatballs and set aside if working in batches.
- Simmer the Marinara Sauce: While your meatballs are searing, pour 32 ounces of your favorite marinara sauce into a separate saucepan. Place it over medium-low heat, allowing it to gently warm through. A slow simmer ensures the sauce is ready to absorb the rich flavors of the meatballs and prevents it from scorching.
- Combine Meatballs and Marinara: Once all your meatballs have been seared to a golden-brown perfection, carefully transfer them from the skillet into the simmering marinara sauce. Stir gently to ensure all meatballs are coated in the luscious sauce. Allow the meatballs to simmer in the marinara for approximately 20 minutes, or until they are fully cooked through and have had a chance to absorb the wonderful flavors of the sauce. This simmering process makes them incredibly tender and flavorful.
- Preheat Oven and Prepare Rolls: Set your oven to the broil setting (typically “high broil”). Alternatively, if you’re less comfortable with broiling, preheat your oven to 400 degrees Fahrenheit (200°C). If your sub or hoagie rolls are not pre-cut, slice them lengthwise, being careful not to cut all the way through, creating a hinge. Place the cut rolls onto a baking sheet. Broil for 3-4 minutes (watch them *very* closely as broilers vary and can burn quickly!) or toast at 400°F for 8 minutes. This crucial step prevents the bread from becoming soggy when loaded with saucy meatballs and adds a satisfying crispness.
- Assemble and Melt: Remove the toasted rolls from the oven. Generously fill each roll with several of the juicy meatballs and plenty of the delicious marinara sauce. Don’t be shy with the sauce – it’s part of the magic! Finally, top each sub with liberal slices of fresh mozzarella cheese. Return the assembled subs to the oven and broil for another 2-3 minutes (or bake at 400°F for 5-6 minutes), just until the fresh mozzarella is beautifully melted, bubbly, and slightly golden.
- Serve Immediately: With the cheese perfectly melted and everything warm and inviting, these meatball subs are best enjoyed fresh from the oven. Sink your teeth into these ultimate Italian meatball subs and savor every single bite. Pure comfort food at its finest!

Expert Tips for the Best Meatball Subs
Achieving the perfect meatball sub involves a few key details that can truly elevate your experience. Here are some expert tips to ensure your subs are nothing short of spectacular:
- Homemade vs. Frozen Meatballs: While convenience often calls for frozen meatballs, and you can absolutely use them for a quicker meal, we strongly encourage you to try making your own for this recipe. The blend of ground beef and Italian sausage, combined with fresh seasonings, creates a depth of flavor and tender texture that simply can’t be matched by store-bought frozen options. If you have the time, the difference is truly worth the effort.
- Enhance Your Rolls: Before toasting your hoagie rolls, consider brushing the insides with a little olive oil or, for an extra burst of flavor, some homemade garlic butter. This adds another layer of deliciousness and creates an even crispier, more satisfying texture that stands up beautifully to the saucy meatballs.
- Customize Your Cheese and Sauce: While we firmly believe fresh mozzarella and classic marinara are the ultimate combination for meatball subs, feel free to personalize your creation! Experiment with other cheeses like sharp provolone for a tangier bite, or grated Parmesan cheese mixed into the mozzarella for added saltiness. As for the sauce, a creamy vodka sauce could offer a delightful twist, or even a spicy arrabbiata if you love heat.
- Don’t Skip the Toasting Step (Twice!): This is a crucial step! Toasting the buns *before* adding the meatballs and sauce is essential to create a barrier that prevents them from becoming soggy. The heat crisps the bread, giving it structure. The second toasting, after assembly, is necessary to melt that gorgeous fresh mozzarella into a gooey, irresistible blanket over your meatballs. Don’t cut corners here!
- Uniform Meatball Size: When forming your meatballs, aim for consistent 1-inch sizes. This ensures they cook evenly and thoroughly. Irregularly sized meatballs can lead to some being overcooked and dry, while others might still be undercooked.
- Avoid Overcrowding the Pan: When searing your meatballs, work in batches if necessary. Overcrowding the skillet will lower the pan’s temperature, causing the meatballs to steam rather than sear and brown. A good sear is vital for developing that rich, savory crust.
- Finish with Fresh Herbs: For a sophisticated touch and a burst of fresh flavor, garnish your finished meatball subs with some chopped fresh herbs. Fresh basil or fresh parsley are excellent choices, adding a vibrant color and aromatic quality that brightens the entire dish.
Make Ahead, Storing, and Freezing
Planning ahead or dealing with leftovers doesn’t have to be a challenge. Here’s how to manage your Italian meatball subs:
Make Ahead: This recipe is wonderfully adaptable for meal prep. You can prepare and cook the meatballs in the marinara sauce a day or two in advance. Once cooked, allow the meatballs and sauce to cool completely, then transfer them to an airtight container and refrigerate. When you’re ready to serve, simply warm the meatballs and sauce gently on the stovetop, toast your buns, assemble, and enjoy a quick, delicious meal. We do not recommend assembling the meatball subs ahead of time, as the bread will inevitably become soggy from the sauce.
Storing Leftovers: Assembled meatball subs, while delicious fresh, do tend to get a little soggy if stored already put together. For the best quality, we highly recommend storing the cooked meatballs and sauce separately in an airtight container in the refrigerator. They will keep beautifully for 3-4 days, allowing you to assemble fresh, crispy subs whenever a craving strikes. If you do end up with leftover assembled subs, don’t fret! Wrap them tightly in aluminum foil and store them in the fridge for 2-3 days. To reheat, place the foil-wrapped subs in an oven preheated to 400 degrees Fahrenheit (200°C) for about 15 minutes. Then, unwrap them and toast for another 5 minutes to crisp up the bun and melt the cheese again.
Freezing: Meatballs and sauce freeze exceptionally well, making this a great recipe for stocking your freezer. You can freeze the cooked meatballs by themselves, or mixed with the marinara sauce, in freezer-safe bags or containers for up to two months. Label clearly with the date. To freeze assembled subs, wrap each tightly in a layer of plastic wrap, then an additional layer of aluminum foil to prevent freezer burn. They can be stored for 1-2 months. Remember to remove the plastic wrap before reheating! When ready to enjoy, thaw the frozen meatballs and sauce overnight in the fridge, or reheat directly from frozen (this may take longer). For frozen assembled subs, reheat (still wrapped in foil, minus plastic wrap) in a 400°F oven until heated through and cheese is melted, unwrapping for the last few minutes to crisp the bread.

Frequently Asked Questions About Meatball Subs
Meatball subs are hearty and flavorful, making them fantastic on their own, but they also pair wonderfully with a variety of side dishes. For a balanced meal, consider serving them with a light Buttered Vegetables or healthy Oven Roasted Broccoli. Other great options include a simple green salad with vinaigrette, a creamy pasta salad, crispy potato chips or french fries, or even a classic coleslaw. These sides help round out the meal without overpowering the main event.
Meatball subs offer some nutritional benefits; the meatballs are high in protein, and marinara sauce provides antioxidants from tomatoes. However, they can also be quite high in calories and fat, especially if using high-fat ground beef and white bread. To make them healthier, you can opt for whole wheat rolls, substitute ground turkey for ground beef in the meatballs, and use a lower-sodium marinara sauce. Including plenty of vegetable sides can also boost the nutritional value of your meal.
Yes, you can freeze meatball subs for 1-2 months, but it’s generally not recommended for optimal texture, as the bread tends to get soggy upon thawing. For the best results, we suggest freezing the cooked meatballs and sauce separately. You can also freeze your hoagie buns in their original packaging. When you’re ready to enjoy, thaw everything in the refrigerator overnight, then toast the fresh or thawed buns, warm the meatballs and sauce, and assemble your subs for a much fresher experience.
Meatball subs are a classic Italian-American culinary invention. They are believed to have originated in the early 1900s within Italian immigrant communities in the United States, likely as a way to adapt traditional Italian meatballs and sauce into a convenient and portable sandwich format. They quickly became a staple in delis and Italian-American eateries, beloved for their hearty and satisfying nature.

Explore More Delicious Meatball Recipes
- BBQ Pineapple Meatballs
- Crock Pot Grape Jelly Meatballs
- Swedish Meatballs
- Sweet and Sour Meatballs
- Turkey Spinach Meatballs
More Irresistible Sandwich Creations
- Beef Stroganoff Sandwich
- Philly Cheesesteak Sloppy Joes
- French Dip Sandwiches
- BBQ Chicken Sandwich
- Chicken Caprese Sandwich
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Review
Italian Meatball Subs
Ingredients
- 1 pound ground beef – (80/20 will make juicier meatballs but you can use whatever fat % you have on hand)
- 8 oz Italian sausage – I used mild, can use hot for spicier meatballs
- 1/2 cup seasoned bread crumbs
- 2 teaspoons Italian seasoning
- 1 large egg
- 1 teaspoon salt
- 1/2 teaspoon black pepper
- 1/2 teaspoon garlic powder
- 1/2 teaspoon onion powder
- 2 tablespoons olive oil
- 32 oz marinara sauce
- 8 oz fresh mozzarella – sliced
- 8 hoagie buns – or sub rolls
Instructions
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In a medium bowl add the ground beef, Italian sausage, bread crumbs, Italian seasoning, egg, salt, pepper, garlic and onion powder. Mix to combine.
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Portion the meat into 1 inch sized meatballs. (Should make about 32 meatballs).
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Heat a nonstick or cast iron skillet over medium heat. Add the olive oil. Once shimmering add the meatballs to the skillet (you may have to work in batches). Cook on each side for 3-4 minutes (I cook on 3-4 sides).
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Meanwhile, place the marinara sauce in a saucepan set over medium low heat. Once the meatballs are done browning, transfer them to the marinara. Simmer for 20 minutes or until cooked through.
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Preheat oven to broil setting.
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When ready to serve, cut the buns in half, making sure not to cut all the way through. Place the bread on a baking sheet and broil for 3-4 minutes (watch carefully so the bread doesn’t burn). If the broil setting scares you, you can preheat the oven to 400°F and toast the bread for 8 minutes.
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Remove from the oven and place some meatballs and sauce into each bun. Top with the fresh mozzarella.
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Return to the oven and broil for 2-3 minutes or until cheese is melted.
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Serve immediately.
Notes
Leftover assembled meatball subs tend to get soggy, so I would recommend only making as many as you’ll eat. Then, store the meatballs and sauce in an airtight container in the fridge for 3-4 days, assembling fresh subs as needed.
You can substitute ground turkey for turkey meatball subs.
Nutrition